Cannabidiol And Cannabinoid Receptors

Poster on
February 19, 2018


CBD stands for cannabidiol. It is one of the numerous cannabinoids that are found within the Cannabis plant. Recently researchers have been looking into its therapeutic uses with great success. CBD oil is made from plants that are high in CBD and low in THC. The Higher in THC plants are usually reserved for medical marijuana. CBD interacts with are brain but is not psychoactive meaning it does not give its user a High. How it works The human body contains many cannabinoid receptors which are all part of the Endocannabinoid system. This system is involved in a variety of processes, Namely appetite, mood, pain-sensation and memory. There are two parts to the Endocannabinoid system, CB1 and CB2, CB1 is in the brain, these receptors deal with movement, emotions, thinking, appetite, mood as well as many other things. CB2 is in the stomach and is more to do with the immune system. Previously it was believed that when a person took CBD the chemical directly acted on these receptors. With further research and experimentation we have found out that this is not true and that CBD somehow influences the body use more efficiently the cannabinoids it already has.

5 Proven appliances of CBD

Relieves pain and inflammation

CBD is a natural painkiller. It does this by inhibiting neuronal transmission within pain pathways in the brain. In 2012 a study was published in the Journey of Experimental Medicine where it was shown that using CBD significantly reduced inflammation and pain in rodents.

Relieves Anxiety

CBD oil has had great success in treating people suffering from Anxiety. It has been shown to minimize social anxiety and has even been successful in helping people suffering from panic attacks and PTSD. In 2011 a study was done where patients with social anxiety disorder where giving either CBD or a placebo. It was shown that the people who took the CBD had significantly less anxiety and discomfort in their speech while the people that took the placebo actually showed signs of having more anxiety and discomfort.

Relieves Nausea

Research has shown that CBD helps ease nausea and vomiting in patients. In 2012 a study was done that showed that taking CBD helped rid rodents of Nausea and relieved Vomiting. Although this is at low does. If high doses are taken it can actually increase Nausea or have no effect. So dose is important.

Helps Fight Cancer

CBD has anti-tumor effects and can be used along side other treatments to improve results. CBD has been shown to stop cancer cells. It has increased the death rate of cancer cells in both Leukemia and Colon Cancer. It has also been shown to decrease the growth and invasion of human glaucoma which in turn shows us its anti-tumor properties.

Helps Arthritis

Due to the anti inflammatory properties of CBD they can helps provide relief to people suffering from joint pain and swelling as well as helping decrease the future impairment of these joints. When administered to animals with arthritis is was shown to improve the problem. It was also shown to help protect the joints from future damage.

History of CBD

CBD has been coming more and more into mainstream attention as more research is being allowed to take place to reveal its benefits. With all this only beginning to happen people may think that CBD is a new thing, and while the methods to extract it that we use today may very well be new, the use of the plant that CBD comes from goes back as far as records do. Cannabis is one of the first plants that was domesticated by humans, records of its use go back thousands of years, and archaeological evidence of its use goes back even further. It is commonly accepted that cannabis was first grown for its strong and durable fibers that were made to make clothes with. There have been clothes of hemp found at digging sites that have dated back 8 thousand years! At some point in the process of growing cannabis for clothes people realized that the plant is very useful for helping with things like anxiety. In ancient India the plant was known as one of the five magical plants that relieve anxiety.

Emerging in recent history

In 1998 a founder of a pharmaceutical company called GW pharmaceuticals convinced the home office to allow them to try and produce a cannabis based medicine with no psychoactive effects. This allowed for the legal growing of low THC and high CBD plants for medical use and research. This opened up the doors for research that was previously very hard get done legally. How it is made The first thing that is needed when creating high quality CBD oil is good cannabis genetics. A good high CBD strain is need, for example Cannatonic contains a ratio of 1:1 THC to CBD and usually has a content of about 8% CBD. This would be a great plant to make CBD oil with. There are two main ways that the compounds in cannabis are extracted for use and they are Alcohol extraction and CO2 Extraction. Alcohol extraction is the method that was used to create the original CBD oil that was created by Rick Simpson. For this method the plant is soaked in a solvent such as grain alcohol or ethanol. After the material is thoroughly soaked the material is separated from the liquid. The compounds leave the material and stay in the liquid. You then evaporate the solvent off and you will be left with potent oil for use. For CO2 extraction CO2 is forced through the plant material and as it goes through a series of different chambers the pressure causes the cannabinoids to separate. As they separate they are collected in these different chambers. This method is more precise as it allows for the separation of the different kind of cannabinoids although it does take more effort, knowledge and equipment.